VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 
  • Homatropine Bromide EY2477

    Homatropine Bromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.

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  • Aclidinium Bromide EY2479

    Aclidinium Bromide inhibits human muscarinic AChR M1, M2, M3, M4 and M5 with Ki of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM and 0.16 nM, respectively.

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  • Diphemanil Methylsulfate EY2480

    Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR).

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  • Norethindrone EY2484

    Norethindrone is a synthetic progestin, which mimic the actions of the endogenous ovarian hormone progesterone.

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  • Hyoscyamine EY2473

    Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM.

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