Sodium Channel
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane. They are classified according to the trigger that opens the channel for such ions, i.e. either a voltage-change ("Voltage-gated", "voltage-sensitive", or "voltage-dependent" sodium channel also called "VGSCs" or "Nav channel") or a binding of a substance (a ligand) to the channel (ligand-gated sodium channels). In excitable cells such as neurons, myocytes, and certain types of glia, sodium channels are responsible for the rising phase of action potentials.
-
Methimepip dihydrobromide是极度高效的选择性 H3 激动剂。
More
-
LOE 908 hydrochloride是广谱性的离子通道阻断剂， 神经保护活性。
More
-
KC 12291 hydrochloride是口服有效的非典型的 Na+ 通道阻断剂（cardioprotective activity）。
More
-
Ketotifen fumarate是H1 拮抗剂。
More
-
JNJ 5207852 dihydrochloride是高亲和性 H3 受体拮抗剂。
More
