Sodium Channel
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane. They are classified according to the trigger that opens the channel for such ions, i.e. either a voltage-change ("Voltage-gated", "voltage-sensitive", or "voltage-dependent" sodium channel also called "VGSCs" or "Nav channel") or a binding of a substance (a ligand) to the channel (ligand-gated sodium channels). In excitable cells such as neurons, myocytes, and certain types of glia, sodium channels are responsible for the rising phase of action potentials.
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A 943931 dihydrochloride是活性的，选择性 H4 拮抗剂。
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A 887826是活性的 电压依赖型 NaV1。8 通道阻断剂。
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A 331440 dihydrochloride是选择性 H3 拮抗剂。
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4-Methylhistamine dihydrochloride是选择性， 高亲和性 H4 激动剂。
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2-Pyridylethylamine dihydrochloride是H1 受体 激动剂。
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