SGLT
SGLT are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose reabsorption. In the kidneys, 100% of the filtered glucose in the glomerulus has to be reabsorbed along the nephron (98% in PCT, via SGLT2). If the plasma glucose concentration is too high (hyperglycemia), glucose is excreted in urine (glucosuria) because SGLT are saturated with the filtered glucose.
-
AZD 2066是mGlu5 拮抗剂， 口服有效，。
More
-
AZ 12216052是 mGlu8的阳性变构调节剂。
More
-
AMN 082 dihydrochloride是首个选择性 mGlu7 激动剂。
More
-
ACPT-II是竞争性 mGlu 受体拮抗剂。
More
-
ACPT-I是Group III mGlu 激动剂。
More
-
AZD 2066是mGlu5 拮抗剂， 口服有效，。
More
-
AZ 12216052是 mGlu8的阳性变构调节剂。
More
-
AMN 082 dihydrochloride是首个选择性 mGlu7 激动剂。
More
-
ACPT-II是竞争性 mGlu 受体拮抗剂。
More
-
ACPT-I是Group III mGlu 激动剂。
More
-
AZD 2066是mGlu5 拮抗剂， 口服有效，。
More
-
AZ 12216052是 mGlu8的阳性变构调节剂。
More
-
AMN 082 dihydrochloride是首个选择性 mGlu7 激动剂。
More
-
ACPT-II是竞争性 mGlu 受体拮抗剂。
More
-
ACPT-I是Group III mGlu 激动剂。
More
