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SGLT


SGLT are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose reabsorption. In the kidneys, 100% of the filtered glucose in the glomerulus has to be reabsorbed along the nephron (98% in PCT, via SGLT2). If the plasma glucose concentration is too high (hyperglycemia), glucose is excreted in urine (glucosuria) because SGLT are saturated with the filtered glucose. 

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    MTEP hydrochloride是活性选择性 mGlu5 拮抗剂。

    More

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    MSOP是特异性的group III mGlu 拮抗剂。

    More

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    MNI键和的L-glutamate是L-glutamate stable photoreleaser 。

    More

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    More
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