SGLT
SGLT are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose reabsorption. In the kidneys, 100% of the filtered glucose in the glomerulus has to be reabsorbed along the nephron (98% in PCT, via SGLT2). If the plasma glucose concentration is too high (hyperglycemia), glucose is excreted in urine (glucosuria) because SGLT are saturated with the filtered glucose.
-
(2R，4R)-APDC是高选择性 group II 激动剂。
More
-
(1S，3R)-ACPD是Group I/group II mGlu 激动剂。
More
-
(±)-trans-ACPD是Group I/group II mGlu 激动剂。
More
-
(±)-LY 395756是Mixed mGlu2 激动剂/ mGlu3 拮抗剂。
More
-
γDGG是广谱的glutamate的受体拮抗剂。
More
-
(2R，4R)-APDC是高选择性 group II 激动剂。
More
-
(1S，3R)-ACPD是Group I/group II mGlu 激动剂。
More
-
(±)-trans-ACPD是Group I/group II mGlu 激动剂。
More
-
(±)-LY 395756是Mixed mGlu2 激动剂/ mGlu3 拮抗剂。
More
-
γDGG是广谱的glutamate的受体拮抗剂。
More
-
(2R，4R)-APDC是高选择性 group II 激动剂。
More
-
(1S，3R)-ACPD是Group I/group II mGlu 激动剂。
More
-
(±)-trans-ACPD是Group I/group II mGlu 激动剂。
More
-
(±)-LY 395756是Mixed mGlu2 激动剂/ mGlu3 拮抗剂。
More
-
γDGG是广谱的glutamate的受体拮抗剂。
More
