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Potassium Channel


potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms. They form potassium-selective pores that span cell membranes. Furthermore potassium channels are found in most cell types and control a wide variety of cell functions. These channels act to set or reset the resting potential in many cells. In excitable cells, such as neurons, the delayed counterflow of potassium ions shapes the action potential.

  • NS 8593 hydrochloride EI1948

    NS 8593 hydrochloride是选择性 KCa2 (SK) 通道的阴性调节剂（negative modulator）， 抑制 SK 电流。

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  • NS 11021 EI1938

    NS 11021是BKCa (KCa1.1) 通道的激动剂。

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  • NS 19504 EI1940

    NS 19504是BKCa (KCa1.1) 通道的激动剂。

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  • NS 309 EI1942

    NS 309是KCa2，KCa3.1 通道阳性变构的调节剂（positive allosteric modulator。

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  • NS 3623 EI1943

    NS 3623是KV11.1 (hERG) 通道激动剂， 抗心律失常的活性。。

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