P-gp
P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
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Bazedoxifene acetate是活性的，选择性 estrogen 受体 调节剂 (SERM)。
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Alphaxalone是直接激动剂， 加强GABAA受体激动的膜电流。
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Allopregnanolone是GABAA受体阳性变构调节剂。
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Acamprosate calcium是GABA 激动剂，glutamatergic 调节剂。
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AA 29504是GABAA受体的阳性变构调节剂。
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Bazedoxifene acetate是活性的，选择性 estrogen 受体 调节剂 (SERM)。
More
-
Alphaxalone是直接激动剂， 加强GABAA受体激动的膜电流。
More
-
Allopregnanolone是GABAA受体阳性变构调节剂。
More
-
Acamprosate calcium是GABA 激动剂，glutamatergic 调节剂。
More
-
AA 29504是GABAA受体的阳性变构调节剂。
More
