P-gp
P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
-
CGP 54626 hydrochloride是活性的， 选择性 GABAB 拮抗剂。
More
-
CGP 46381是可透血脑屏障的， 选择性 GABAB 拮抗剂。
More
-
CGP 36216 hydrochloride是GABAB 拮抗剂， 对突触前受体展现活性。。
More
-
CGP 35348是选择性，可透血脑屏障的GABAB受体拮抗剂。
More
-
CGP 13501是GABAB 受体阳性调节剂。。
More
-
CGP 54626 hydrochloride是活性的， 选择性 GABAB 拮抗剂。
More
-
CGP 46381是可透血脑屏障的， 选择性 GABAB 拮抗剂。
More
-
CGP 36216 hydrochloride是GABAB 拮抗剂， 对突触前受体展现活性。。
More
-
CGP 35348是选择性，可透血脑屏障的GABAB受体拮抗剂。
More
-
CGP 13501是GABAB 受体阳性调节剂。。
More
