P-gp
P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
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CP 100356 hydrochloride是P-gp 抑制剂。
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Chlormethiazole hydrochloride是增强 GABAA受体功能。
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CGS 20625是Selective, partial agonist for the benzodiazepine binding site of the GABAA receptor。
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CGP 7930是GABAB 受体阳性调节剂。
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CGP 55845 hydrochloride是活性的, 选择性 GABAB 拮抗剂。
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CP 100356 hydrochloride是P-gp 抑制剂。
More
-
Chlormethiazole hydrochloride是增强 GABAA受体功能。
More
-
CGS 20625是Selective, partial agonist for the benzodiazepine binding site of the GABAA receptor。
More
-
CGP 7930是GABAB 受体阳性调节剂。
More
-
CGP 55845 hydrochloride是活性的, 选择性 GABAB 拮抗剂。
More