P-gp


P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
  • CP 100356 hydrochloride EI0854

    CP 100356 hydrochloride是P-gp 抑制剂。

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  • Chlormethiazole hydrochloride EI0778

    Chlormethiazole hydrochloride是增强 GABAA受体功能。

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  • CGS 20625 EI0769

    CGS 20625是Selective, partial agonist for the benzodiazepine binding site of the GABAA receptor。

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  • CGP 7930 EI0762

    CGP 7930是GABAB 受体阳性调节剂。

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  • CGP 55845 hydrochloride EI0756

    CGP 55845 hydrochloride是活性的, 选择性 GABAB 拮抗剂。

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  • CP 100356 hydrochloride EI0854

    CP 100356 hydrochloride是P-gp 抑制剂。

    More
  • Chlormethiazole hydrochloride EI0778

    Chlormethiazole hydrochloride是增强 GABAA受体功能。

    More
  • CGS 20625 EI0769

    CGS 20625是Selective, partial agonist for the benzodiazepine binding site of the GABAA receptor。

    More
  • CGP 7930 EI0762

    CGP 7930是GABAB 受体阳性调节剂。

    More
  • CGP 55845 hydrochloride EI0756

    CGP 55845 hydrochloride是活性的, 选择性 GABAB 拮抗剂。

    More
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