P-gp


P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
  • SB 205384 EI2457

    SB 205384是GABAA受体调节剂(SB 205384 could slow current decay)。

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  • Saclofen EI2437

    Saclofen是选择性 GABAB 拮抗剂。

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  • RU 58668 EI2405

    RU 58668是抗雌激素剂(antiestrogen)。

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  • RuBi-GABA EI2410

    RuBi-GABA是Ru group bonding GABA that is excitable by visible wavelength。

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  • Reversan EI2325

    Reversan是选择性 MRP1,P-gp 抑制剂。

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  • SB 205384 EI2457

    SB 205384是GABAA受体调节剂(SB 205384 could slow current decay)。

    More
  • Saclofen EI2437

    Saclofen是选择性 GABAB 拮抗剂。

    More
  • RU 58668 EI2405

    RU 58668是抗雌激素剂(antiestrogen)。

    More
  • RuBi-GABA EI2410

    RuBi-GABA是Ru group bonding GABA that is excitable by visible wavelength。

    More
  • Reversan EI2325

    Reversan是选择性 MRP1,P-gp 抑制剂。

    More
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