P-gp


P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
  • TPMPA EI2803

    TPMPA是选择性GABAA-ρ的拮抗剂。

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  • Tracazolate hydrochloride EI2804

    Tracazolate hydrochloride是亚型选择性的GABAA 的变构的调节剂。

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  • Tramiprosate EI2806

    Tramiprosate是Targets soluble Aβ to decrease amyloid plaque deposition。 也是GABA类似物。

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  • Tiagabine hydrochloride EI2780

    Tiagabine hydrochloride是GABA uptake inhibitor(摄取抑制剂), 抗惊厥剂。

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  • Tianeptine sodium salt EI2781

    Tianeptine sodium salt是Tiagabine hydrochloride is a GABA uptake inhibitor; anticonvulsant activity.。

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  • TPMPA EI2803

    TPMPA是选择性GABAA-ρ的拮抗剂。

    More
  • Tracazolate hydrochloride EI2804

    Tracazolate hydrochloride是亚型选择性的GABAA 的变构的调节剂。

    More
  • Tramiprosate EI2806

    Tramiprosate是Targets soluble Aβ to decrease amyloid plaque deposition。 也是GABA类似物。

    More
  • Tiagabine hydrochloride EI2780

    Tiagabine hydrochloride是GABA uptake inhibitor(摄取抑制剂), 抗惊厥剂。

    More
  • Tianeptine sodium salt EI2781

    Tianeptine sodium salt是Tiagabine hydrochloride is a GABA uptake inhibitor; anticonvulsant activity.。

    More
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