P-gp
P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
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(±)-Nipecotic acid是GABA uptake inhibitor（摄取抑制剂）。
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(-)-Bicuculline methochloride是水溶性 GABAA 拮抗剂。
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(-)-Bicuculline methiodide是Water-soluble GABAA 拮抗剂。
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LX-4211是SGLT1/2抑制剂，是抗糖尿病剂。
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α-Estradiol是内源性 estrogen 受体激动剂。
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(±)-Nipecotic acid是GABA uptake inhibitor（摄取抑制剂）。
More
-
(-)-Bicuculline methochloride是水溶性 GABAA 拮抗剂。
More
-
(-)-Bicuculline methiodide是Water-soluble GABAA 拮抗剂。
More
-
LX-4211是SGLT1/2抑制剂，是抗糖尿病剂。
More
-
α-Estradiol是内源性 estrogen 受体激动剂。
More
