Oct-4


Oct-4 transcription factor(Oct3/4,POU5F1) is initially active as a maternal factor in the oocyte but remains active in embryos throughout the preimplantation period. Oct-4 expression is associated with an undifferentiated phenotype and tumors. Gene knockdown of Oct-4 promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal. Oct-4 can form a heterodimer with Sox2, so that these two proteins bind DNA together.
  • CD 437 EI0719

    CD 437是RARγ-选择性激动剂。

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  • CD 3254 EI0718

    CD 3254是活性选择性 RXRα 激动剂。

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  • CD 2665 EI0717

    CD 2665是选择性 RARβ/γ 拮抗剂。

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  • CD 2314 EI0716

    CD 2314是选择性 RARβ 激动剂。

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  • CD 1530 EI0715

    CD 1530是活性的,选择性 RARγ 激动剂。

    More
  • CD 437 EI0719

    CD 437是RARγ-选择性激动剂。

    More
  • CD 3254 EI0718

    CD 3254是活性选择性 RXRα 激动剂。

    More
  • CD 2665 EI0717

    CD 2665是选择性 RARβ/γ 拮抗剂。

    More
  • CD 2314 EI0716

    CD 2314是选择性 RARβ 激动剂。

    More
  • CD 1530 EI0715

    CD 1530是活性的,选择性 RARγ 激动剂。

    More
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