Oct-4


Oct-4 transcription factor(Oct3/4,POU5F1) is initially active as a maternal factor in the oocyte but remains active in embryos throughout the preimplantation period. Oct-4 expression is associated with an undifferentiated phenotype and tumors. Gene knockdown of Oct-4 promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal. Oct-4 can form a heterodimer with Sox2, so that these two proteins bind DNA together.
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    Docosahexaenoic acid是RXR 激动剂。

    More
  • Dihydrexidine hydrochloride EI0980

    Dihydrexidine hydrochloride是选择性 D1样激动剂。

    More
  • D-Amphetamine sulfate EI0926

    D-Amphetamine sulfate是诱导dopamine, 5-HT,noradrenalin的释放。

    More
  • CY 208-243 EI0893

    CY 208-243是选择性D1样激动剂。

    More
  • Clozapine EI0829

    Clozapine是Dopamine 拮抗剂 具有部分 D4 选择性。 也是5-HT2A/2C 拮抗剂。

    More
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