Oct-4
Oct-4 transcription factor(Oct3/4,POU5F1) is initially active as a maternal factor in the oocyte but remains active in embryos throughout the preimplantation period. Oct-4 expression is associated with an undifferentiated phenotype and tumors. Gene knockdown of Oct-4 promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal. Oct-4 can form a heterodimer with Sox2, so that these two proteins bind DNA together.
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Acitretin, a retinoid that binds to nuclear receptors and regulates gene expression, is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. Acitretin is a systemic retinoid drug used in the treatment of severe psoriasis. Synthetic retinoid that is a metabolite of etretinate. Preferentially binds to cellular retinoic acid binding proteins (CRABPs). Acitretin is a second generation retinoid used for psoriasis.
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HX 531是活性的 RXR 拮抗剂。
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HX 630是RXR synergist。
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Haloperidol hydrochloride是拮抗剂， 部分 D2 选择性。
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GSK 789472 hydrochloride是D3 拮抗剂。 也是D2部分激动剂。
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Acitretin, a retinoid that binds to nuclear receptors and regulates gene expression, is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. Acitretin is a systemic retinoid drug used in the treatment of severe psoriasis. Synthetic retinoid that is a metabolite of etretinate. Preferentially binds to cellular retinoic acid binding proteins (CRABPs). Acitretin is a second generation retinoid used for psoriasis.
More
-
HX 531是活性的 RXR 拮抗剂。
More
-
HX 630是RXR synergist。
More
-
Haloperidol hydrochloride是拮抗剂， 部分 D2 选择性。
More
-
GSK 789472 hydrochloride是D3 拮抗剂。 也是D2部分激动剂。
More
