Oct-4
Oct-4 transcription factor(Oct3/4,POU5F1) is initially active as a maternal factor in the oocyte but remains active in embryos throughout the preimplantation period. Oct-4 expression is associated with an undifferentiated phenotype and tumors. Gene knockdown of Oct-4 promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal. Oct-4 can form a heterodimer with Sox2, so that these two proteins bind DNA together.
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A 68930 hydrochloride是活性的， 选择性 D1样激动剂。
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A 412997 dihydrochloride是选择性 D4 激动剂。
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7-Hydroxy-PIPAT maleate是D3 激动剂 (D3 > D2)。
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7-Hydroxy-DPAT hydrobromide是Dopamine 激动剂 (D3 ≥ D2 < > D4)。
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3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride是活性的 dopamine uptake inhibitor （摄取抑制剂）。
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A 68930 hydrochloride是活性的， 选择性 D1样激动剂。
More
-
A 412997 dihydrochloride是选择性 D4 激动剂。
More
-
7-Hydroxy-PIPAT maleate是D3 激动剂 (D3 > D2)。
More
-
7-Hydroxy-DPAT hydrobromide是Dopamine 激动剂 (D3 ≥ D2 < > D4)。
More
-
3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride是活性的 dopamine uptake inhibitor （摄取抑制剂）。
More
