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NMDA


NMDA (N-Methyl-D-aspartic acid or N-Methyl-D-aspartate) is an amino acid derivative that acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Unlike glutamate, NMDA only binds to and regulates the NMDA receptor and has no effect on other glutamate receptors. NMDA is an excitotoxin,this trait has applications in behavioral neuroscience research. 

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    (2R，3S)-Chlorpheg是弱效的NMDA拮抗剂。

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  • (±)-1-(1，2-Diphenylethyl)piperidine maleate EI0073

    (±)-1-(1，2-Diphenylethyl)piperidine maleate是NMDA 拮抗剂，作用于离子通道位点。

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  • Avosentan EY2836

    Avosentan是内皮素（ETA）受体拮抗剂。

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  • XMD8-87 EY2831

    XMD8-87是有效的TNK2抑制剂，对D163E和R806Q突变型TNK2的IC50值分别为38 nM和113 nM。

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  • threo Ifenprodil hemitartrate EI2776

    threo Ifenprodil hemitartrate是NR2B-选择性NMDA拮抗剂，也是 σ 激动剂。

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