NMDA
NMDA (N-Methyl-D-aspartic acid or N-Methyl-D-aspartate) is an amino acid derivative that acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Unlike glutamate, NMDA only binds to and regulates the NMDA receptor and has no effect on other glutamate receptors. NMDA is an excitotoxin,this trait has applications in behavioral neuroscience research.
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TCS 46b是口服有效的亚型选择性的NR1A/NR2B拮抗剂。
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TCN 201是选择性 NR1/NR2A 受体拮抗剂。
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TCN 213是NMDA 拮抗剂,对NR2A选择性强于对NR2B。
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TCN 237 dihydrochloride是高活性选择性的NR2B拮抗剂。
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Synthalin sulfate是非竞争性的NMDA 拮抗剂。
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