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Ion Pumps/Transporters


Ion pumps/transporters are transmembrane proteins that allow ion flux across biological membranes against their concentration gradient. Ion pumps require energy usually from ATP hydrolysis, whilst exchangers use the energy established by the concentration gradient of another ion. They belong to the ATPase and solute carrier families and are important for maintaining the correct concentrations of various ions within the appropriate subcellular and intercellular compartments. Ion pumps/transporters include:
Ca2+-ATPase ;    H+,K+-ATPase;    H+-ATPase;    K+/Cl- Cotransporter 2 ;   Monocarboxylate Transporters;
Na+/Ca2+ Exchanger ;   Na+/H+ Exchanger ;   Na+/K+ ATPase ;   Na+/K+/Cl- Symporter.

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    A 412997 dihydrochloride是选择性 D4 激动剂。

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  • 7-Hydroxy-PIPAT maleate EI0308

    7-Hydroxy-PIPAT maleate是D3 激动剂 (D3 > D2)。

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  • 7-Hydroxy-DPAT hydrobromide EI0307

    7-Hydroxy-DPAT hydrobromide是Dopamine 激动剂 (D3 ≥ D2 < > D4)。

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  • 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride EI0272

    3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride是活性的 dopamine uptake inhibitor （摄取抑制剂）。

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  • 3'-Fluorobenzylspiperone maleate EI0266

    3'-Fluorobenzylspiperone maleate是D2样受体的配体。

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