Gardos Channel
Gardos Channel (Potassium intermediate/small conductance calcium-activated channel, subfamily N,KCNN4) is a human gene encoding the KCa3.1 protein. The KCa3.1 protein is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
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SBHA是HDAC(Histone deacetylase)抑制剂。
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Radicicol是Hsp90 抑制剂。有抗真菌和抗细菌的活性。。
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Pyroxamide是组蛋白去乙酰抑制剂HDAC (histone deacetylase)。
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NSC 3852是组蛋白脱乙酰酶抑制剂HDAC(histone deacetylase)。
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MI 192是活性的,选择性HDAC2/3抑制剂。
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