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A synthetic peptide that inhibits Granzyme B.
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Peptide sequence shown to be preferred recognition motif for the serine protease granzyme B. Fluorogenic substrate.
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ILK-IN-1 is a novel ILK inhibitor with IC50 of 0.6 μM.
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CX-3543 is a fluoroquinolone derivative with antineoplastic activity. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template, a critical interaction for rRNA biogenesis that is overexpressed in cancer cells; disruption of this G-quadruplex DNA:protein interaction in aberrant rRNA biogenesis may result in the inhibition of ribosome synthesis and tumor cell apoptosis.
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FPS-ZM1 is a blood-brain-barrier permeant, non-toxic, tertiary amide compound which is a high affinity RAGE-specific inhibitor, blocking Aβ binding to the V domain of RAGE.
More
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A synthetic peptide that inhibits Granzyme B.
More
-
Peptide sequence shown to be preferred recognition motif for the serine protease granzyme B. Fluorogenic substrate.
More
-
ILK-IN-1 is a novel ILK inhibitor with IC50 of 0.6 μM.
More
-
CX-3543 is a fluoroquinolone derivative with antineoplastic activity. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template, a critical interaction for rRNA biogenesis that is overexpressed in cancer cells; disruption of this G-quadruplex DNA:protein interaction in aberrant rRNA biogenesis may result in the inhibition of ribosome synthesis and tumor cell apoptosis.
More
-
FPS-ZM1 is a blood-brain-barrier permeant, non-toxic, tertiary amide compound which is a high affinity RAGE-specific inhibitor, blocking Aβ binding to the V domain of RAGE.
More
