NF-κB
NF-κB is important in regulating cellular responses because it belongs to the category of "rapid-acting" primary transcription factors, i.e., transcription factors that are present in cells in an inactive state and do not require new protein synthesis in order to become activated (other members of this family include transcription factors such as c-Jun, STATs, and nuclear hormone receptors). This allows NF-κB to be a first responder to harmful cellular stimuli. Known inducers of NF-κB activity are highly variable and include reactive oxygen species (ROS), tumor necrosis factor alpha (TNFα), interleukin 1-beta (IL-1β), bacterial lipopolysaccharides (LPS), isoproterenol, cocaine, and ionizing radiation.
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Triptolide是由中草药-雷公藤中提取的免疫抑制剂。
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Andrographolide是一个不可逆的NF-κB通路拮抗剂，能阻止T细胞体外活化，抗病毒，抗炎，抗凋亡，降脂性能。
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Triptolide是由中草药-雷公藤中提取的免疫抑制剂。
More
-
Andrographolide是一个不可逆的NF-κB通路拮抗剂，能阻止T细胞体外活化，抗病毒，抗炎，抗凋亡，降脂性能。
More
