HIF
Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia. HIF plays a central role in the regulation of human metabolism.HIF activity is involved in angiogenesis required for cancer tumor growth, so HIF inhibitors are under investigation for anti-cancer effects.
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PX-478是缺氧诱导因子1a的抑制剂, IC50值为20-30uM, 可提高前列腺癌细胞的辐射敏感性。
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PX-478是缺氧诱导因子1a的抑制剂, IC50值为20-30uM, 可提高前列腺癌细胞的辐射敏感性。
More