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Transferase


The transferase is any one of a class of enzymes that enact the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor). They are involved in hundreds of different biochemical pathways throughout biology, and are integral to some of life’s most important processes.

  • FTI 277 HCl EY1312

    FTI-277盐酸盐是法尼基转移酶FTase抑制剂，高效Ras CAAX肽模拟物，可抑制H-Ras和K-Ras信号转导。

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  • LB42708 EY1148

    LB42708 是一种口服有效的 farnesyltransferase (FTase) 抑制剂。

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  • Tolcapone EY1061

    Tolcapone是一种有效和选择性的可逆硝基酚类儿茶酚-O-甲基转移酶(COMT)抑制剂，Ki为30nM。

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  • A922500 EY0934

    A922500是人类和小鼠DGAT-1抑制剂，IC50分别为7 nM和24 nM，比作用于相关的酰基转移酶，hERG及抗靶面板的选择性高。

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  • Tipifarnib EY0326

    Tipifarnib是特异的法尼基转移酶抑制剂，IC50为0.6 nM。

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