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RARs/RXR


RAR (The retinoic acid receptor) is a type of nuclear receptor which can also act as a transcription factor that is activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-alpha, RAR-beta, and RAR-gamma. Each receptor isoform has several splice variants: four- for alpha, four- for beta, and two- for gamma. RXR (The retinoid X receptor) is a type of nuclear receptor that is activated by 9-cis retinoic acid. There are three retinoic X receptors (RXR): RXR-alpha, RXR-beta, and RXR-gamma. RXR heterodimerizes with subfamily 1 nuclear receptors including CAR, FXR, LXR, PPAR, PXR, RAR, TR, and VDR.

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    AC 55649是选择性 RARβ2 激动剂。

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  • AC 261066 EI0365

    AC 261066是RARβ2 激动剂。

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  • Tazarotene EI2681

    Tazarotene是具有乙炔维A酸（acetylenic retinoid）受体选择性， 同retinoid acid receptors(RAR)-β和-γ相互作用。

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  • MM 11253 EI1736

    MM 11253是RARγ-选择性拮抗剂。

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  • LG 101506 EI1542

    LG 101506是选择性 RXR 调节剂。

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