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RARs/RXR


RAR (The retinoic acid receptor) is a type of nuclear receptor which can also act as a transcription factor that is activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-alpha, RAR-beta, and RAR-gamma. Each receptor isoform has several splice variants: four- for alpha, four- for beta, and two- for gamma. RXR (The retinoid X receptor) is a type of nuclear receptor that is activated by 9-cis retinoic acid. There are three retinoic X receptors (RXR): RXR-alpha, RXR-beta, and RXR-gamma. RXR heterodimerizes with subfamily 1 nuclear receptors including CAR, FXR, LXR, PPAR, PXR, RAR, TR, and VDR.

  • CD 437 EI0719

    CD 437是RARγ-选择性激动剂。

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  • CD 3254 EI0718

    CD 3254是活性选择性 RXRα 激动剂。

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  • CD 2665 EI0717

    CD 2665是选择性 RARβ/γ 拮抗剂。

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  • CD 2314 EI0716

    CD 2314是选择性 RARβ 激动剂。

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  • CD 1530 EI0715

    CD 1530是活性的，选择性 RARγ 激动剂。

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