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S1P Receptor


The sphingosine-1-phosphate receptors are a class of G protein-coupled receptors that are targets of the lipid signalling molecule Sphingosine-1-phosphate (S1P). They are divided into five subtypes: S1PR1, S1PR2, S1PR3, S1PR4 and S1PR5. The sphingosine-1-phosphate receptors regulate fundamental biological processes such as cell proliferation, angiogenesis, migration, cytoskeleton organization, endothelial cell chemotaxis, immune cell trafficking and mitogenesis. Sphingosine-1-phosphate receptors are also involved in immune-modulation and directly involved in suppression of innate immune responses from T cells.

  • CYM 50260 EI0902

    CYM 50260是活性选择性 S1P4 激动剂。

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  • A 971432 EI0348

    A 971432是活性的，选择性 S1P5 激动剂。

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  • W146 EI2926

    W146是活性选择性S1P1受体拮抗剂。

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  • VPC 23019 EI2891

    VPC 23019是S1P1的S1P3 拮抗剂。

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  • TY 52156 EI2826

    TY 52156是S1P3 受体的拮抗剂。

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