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Opioid Receptor


Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands.[1][2][3] The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are ~40% identical to somatostatin receptors (SSTRs). Opioid receptors are distributed widely in the brain, and are found in the spinal cord and digestive tract.The endogenous opioid system is thought to be important in mediating complex social behaviors involved in the formation of stable, emotionally committed relationships.

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    Fentanyl citrate是活性的,选择性 μ 激动剂。

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    Diprenorphine是非选择性 opioid 拮抗剂。

    More
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    DIPPA hydrochloride是选择性不可逆的 κ 拮抗剂。

    More
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    Cyprodime hydrochloride是选择性 μ 拮抗剂。

    More
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    Clocinnamox mesylate是不可逆 μ 拮抗剂(Irreversible μ antagonist)。

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  • Fentanyl citrate EI1115

    Fentanyl citrate是活性的,选择性 μ 激动剂。

    More
  • Diprenorphine EI0997

    Diprenorphine是非选择性 opioid 拮抗剂。

    More
  • DIPPA hydrochloride EI0996

    DIPPA hydrochloride是选择性不可逆的 κ 拮抗剂。

    More
  • Cyprodime hydrochloride EI0912

    Cyprodime hydrochloride是选择性 μ 拮抗剂。

    More
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    Clocinnamox mesylate是不可逆 μ 拮抗剂(Irreversible μ antagonist)。

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