mAChR
MAChRs (Muscarinic acetylcholine receptors) are acetylcholine receptors that form G protein-receptor complexes in the cell membranes of certain neurons and other cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. Muscarinic receptors were named as such because they are more sensitive to muscarine than to nicotine. Their counterparts are nicotinic acetylcholine receptors (nAChRs), receptor ion channels that are also important in the autonomic nervous system. Many drugs and other substances (for example pilocarpine and scopolamine) manipulate these two distinct receptors by acting as selective agonists or antagonists.
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VU 0238429是选择性M5受体阳性变构的调节剂（positive allosteric modulator）。
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Tropicamide是选择性M4 muscarinic受体拮抗剂。
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Tolterodine L-tartrate是活性非选择性muscarinic的受体拮抗剂。
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Tiotropium bromide是活性的muscarinic受体的拮抗剂。
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Telenzepine dihydrochloride是活性选择性 M1 拮抗剂。
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VU 0238429是选择性M5受体阳性变构的调节剂（positive allosteric modulator）。
More
-
Tropicamide是选择性M4 muscarinic受体拮抗剂。
More
-
Tolterodine L-tartrate是活性非选择性muscarinic的受体拮抗剂。
More
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Tiotropium bromide是活性的muscarinic受体的拮抗剂。
More
-
Telenzepine dihydrochloride是活性选择性 M1 拮抗剂。
More
