mAChR
MAChRs (Muscarinic acetylcholine receptors) are acetylcholine receptors that form G protein-receptor complexes in the cell membranes of certain neurons and other cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. Muscarinic receptors were named as such because they are more sensitive to muscarine than to nicotine. Their counterparts are nicotinic acetylcholine receptors (nAChRs), receptor ion channels that are also important in the autonomic nervous system. Many drugs and other substances (for example pilocarpine and scopolamine) manipulate these two distinct receptors by acting as selective agonists or antagonists.
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AF-DX 384是活性的 M2/M4 拮抗剂。
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AF-DX 116是选择性 M2 拮抗剂。
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5-Methylfurmethiodide是活性的 muscarinic 激动剂。
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4-DAMP是Muscarinic M3 拮抗剂。
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4，4-Pentamethylenepiperidine hydrochloride是M2 proton 通道阻断剂。
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AF-DX 384是活性的 M2/M4 拮抗剂。
More
-
AF-DX 116是选择性 M2 拮抗剂。
More
-
5-Methylfurmethiodide是活性的 muscarinic 激动剂。
More
-
4-DAMP是Muscarinic M3 拮抗剂。
More
-
4，4-Pentamethylenepiperidine hydrochloride是M2 proton 通道阻断剂。
More
