Home > Signal Pathway > GPCR & G Protein > mAChR

mAChR


MAChRs (Muscarinic acetylcholine receptors) are acetylcholine receptors that form G protein-receptor complexes in the cell membranes of certain neurons and other cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. Muscarinic receptors were named as such because they are more sensitive to muscarine than to nicotine. Their counterparts are nicotinic acetylcholine receptors (nAChRs), receptor ion channels that are also important in the autonomic nervous system. Many drugs and other substances (for example pilocarpine and scopolamine) manipulate these two distinct receptors by acting as selective agonists or antagonists.

  • Homatropine Methylbromide EY2476

    Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.

    More

  • Oxybutynin chloride EY2447

    Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.

    More

  • Otilonium Bromide EY2434

    Otilonium bromide is an antimuscarinic.

    More

  • Bethanechol chloride EY2380

    Bethanechol chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors.

    More

  • Fesoterodine Fumarate EY2370

    Fesoterodine fumarate (Toviaz) is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist.

    More

  • Homatropine Methylbromide EY2476

    Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.

    More

  • Oxybutynin chloride EY2447

    Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.

    More

  • Otilonium Bromide EY2434

    Otilonium bromide is an antimuscarinic.

    More

  • Bethanechol chloride EY2380

    Bethanechol chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors.

    More

  • Fesoterodine Fumarate EY2370

    Fesoterodine fumarate (Toviaz) is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist.

    More
    • Current page3, Total Pages12, Total Record59 First Prev 12345 Next Last Goto
More