NMDAR
NMDAR(N-methyl-D-aspartate receptor) is a glutamate receptor and ion channel protein found in nerve cells. It is activated when glutamate and glycine (or D-serine) bind to it, and when activated it allows positively charged ions to flow through the cell membrane. The NMDA receptor is very important for controlling synaptic plasticity and memory function. The NMDAR is a specific type of ionotropic glutamate receptor.
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(R)-4-Carboxyphenylglycine是Moderately potent NMDA receptor antagonist.(NMDA受体拮抗剂)。
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(R)-(+)-HA-966是NMDA 部分激动剂/拮抗剂,作用在甘氨酸位点。。
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(2R,3S)-Chlorpheg是弱效的NMDA拮抗剂。
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(±)-1-(1,2-Diphenylethyl)piperidine maleate是NMDA 拮抗剂,作用于离子通道位点。
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threo Ifenprodil hemitartrate是NR2B-选择性NMDA拮抗剂,也是 σ 激动剂。
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