mAChR
MAChRs (Muscarinic acetylcholine receptors) are acetylcholine receptors that form G protein-receptor complexes in the cell membranes of certain neurons and other cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. Muscarinic receptors were named as such because they are more sensitive to muscarine than to nicotine. Their counterparts are nicotinic acetylcholine receptors (nAChRs), receptor ion channels that are also important in the autonomic nervous system. Many drugs and other substances (for example pilocarpine and scopolamine) manipulate these two distinct receptors by acting as selective agonists or antagonists.
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Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
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Otilonium bromide is an antimuscarinic.
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Bethanechol chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors.
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Fesoterodine fumarate (Toviaz) is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist.
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DAU 5884 hydrochloride是M3 受体拮抗剂。
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Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
More
-
Otilonium bromide is an antimuscarinic.
More
-
Bethanechol chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors.
More
-
Fesoterodine fumarate (Toviaz) is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist.
More
-
DAU 5884 hydrochloride是M3 受体拮抗剂。
More
