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Amyloid beta(Aβ)


Amyloid beta(Aβ) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. 
  • J 147 EI1379

    J 147是J 147 reduces Aβ40,Aβ42 levels(neuroprotective,neurotrophic compound)。

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  • EUK 134 EY1456

    EUK 134是一种合成的超氧化物歧化酶(SOD)/过氧化氢酶类似物,具有强效的抗氧化活性,且抑制β-amyloid(β-淀粉样蛋白)和相关的淀粉样纤维形成。

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  • MK-0752 EY0340

    MK-0752是一种适度有效的γ-secretase(γ-分泌酶)抑制剂,降低Aβ40产量,IC50为5 nM。

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