nAChR
nAChRs (Nicotinic acetylcholine receptors) are neuron receptor proteins that respond to the neurotransmitter acetylcholine. They are particularly responsive to nicotine. Nicotinic receptors also respond to drugs, including the nicotinic receptor agonist nicotine. As ionotropic receptors, nAChRs are directly linked to ion channels and do not use second messengers (as metabotropic receptors do). Nicotinic acetylcholine receptors are the best-studied of the ionotropic receptors.
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TC 2559 difumarate是α4β2受体的选择性部分激动剂。
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SSR 180711 hydrochloride是α7 nAChR的部分激动剂。
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SR 16584是选择性 α3β4 nAChR 拮抗剂。
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SIB 1508Y maleate是α4β2, α2β4, α4β4和α3β4 nACh的活性激动剂。
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SIB 1553A hydrochloride是亚型选择性的nAChR激动剂。
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