Cannabinoid Receptor
Cannabinoid receptors, located throughout the body, are part of the Endocannabinoid system which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory.
Cannabinoid receptors are of a class of cell membrane receptors under the G protein-coupled receptor superfamily. As is typical of G protein-coupled receptors, the cannabinoid receptors contain seven transmembrane spanning domains. Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, produced by the mammillary body; plant cannabinoids; and synthetic cannabinoids. There are currently two known subtypes of cannabinoid receptors, termed CB1 and CB2.
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MDA 19是CB2 激动剂。
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LY 320135是选择性CB1受体拮抗剂/反向激动剂。
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Leelamine hydrochloride是CB1 激动剂。
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L-759，633是高亲和性， 选择性 CB2 激动剂。
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L-759，656是高 选择性 CB2 激动剂。
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