Adenosine Receptor
The adenosine receptors (P1 receptors) are a class of purinergic G protein-coupled receptors with adenosine as endogenous ligand. In humans, there are four types of adenosine receptors(A1,A2A ,A2B,A3). Each is encoded by a separate gene and has different functions, although with some overlap. For instance, both A1 receptors and A2A play roles in the heart, regulating myocardial oxygen consumption and coronary blood flow, while the A2A receptor also has broader anti-inflammatory effects throughout the body. These two receptors also have important roles in the brain, regulating the release of other neurotransmitters such as dopamine and glutamate, while the A2B and A3 receptors are located mainly peripherally and are involved in processes such as inflammation and immune responses.
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Dilazep dihydrochloride是Adenosine uptake inhibitor（摄取抑制剂）。
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Dansyl-NECA是活性选择性荧光 adenosine A1 激动剂（fluorescent adenosine A1 agonist）。
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CV 1808是非选择性 adenosine A2 受体激动剂。
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CGS 15943是活性的adenosine受体拮抗剂。
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CGH 2466 dihydrochloride是A1， A2B 和 A3 拮抗剂，p38 MAPK和PDE4的抑制剂。
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