PKC
PKC (Protein kinase C) is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family. PKC enzymes in turn are activated by signals such as increases in the concentration of diacylglycerol (DAG) or calcium ions (Ca2+). Hence PKC enzymes play important roles in several signal transduction cascades.
The PKC family consists of fifteen isozymes in humans. They are divided into three subfamilies, based on their second messenger requirements: conventional (or classical), novel, and atypical.
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PEP 005是Protein kinase C 激动剂。
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Oncrasin 1是Oncrasin 1 induces abnormal nuclear aggregation of PKCι， proapoptotic。
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LY 333531 hydrochloride是Protein kinase C 抑制剂， β isozymes选择性。
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K-252c是Protein kinase C 抑制剂。
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Enzastaurin (LY317615)是PKCβ选择性抑制剂，IC50为6 nM，比对PKCα，PKCγ和PKCε的抑制性强6-20倍。
More
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PEP 005是Protein kinase C 激动剂。
More
-
Oncrasin 1是Oncrasin 1 induces abnormal nuclear aggregation of PKCι， proapoptotic。
More
-
LY 333531 hydrochloride是Protein kinase C 抑制剂， β isozymes选择性。
More
-
K-252c是Protein kinase C 抑制剂。
More
-
Enzastaurin (LY317615)是PKCβ选择性抑制剂，IC50为6 nM，比对PKCα，PKCγ和PKCε的抑制性强6-20倍。
More
