Potassium Channel
potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms. They form potassium-selective pores that span cell membranes. Furthermore potassium channels are found in most cell types and control a wide variety of cell functions. These channels act to set or reset the resting potential in many cells. In excitable cells, such as neurons, the delayed counterflow of potassium ions shapes the action potential.
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Doxofylline是一种磷酸二酯酶抑制剂,是黄嘌呤衍生物,用于治疗哮喘。
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Icariin(Ieariline)是一种黄酮类中药淫羊藿主要成分,具有多种生物学特性,包括抗炎,神经调节和保护活性等。
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Mitiglinide Calcium是KATP通道拮抗剂,具有抗2型糖尿病活性。
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Deltarasin能抑制KRAS与PDEδ的相互作用,结合PDEδ的Kd为41 nM,能阻断致癌的KRAS信号通路。
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Anagrelide(BL4162A)盐酸盐对血小板增多症有效。
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