Potassium Channel
potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms. They form potassium-selective pores that span cell membranes. Furthermore potassium channels are found in most cell types and control a wide variety of cell functions. These channels act to set or reset the resting potential in many cells. In excitable cells, such as neurons, the delayed counterflow of potassium ions shapes the action potential.
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Pentoxifylline是PDE 抑制剂。
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PD 118057是选择性 KV11.1 (hERG) 通道激动剂。
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P1075是活性的 Kir6 (KATP) 通道开启剂(channel opener)。
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NS 5806是KV4.3 channel 激动剂。
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NS 6180是活性的 KCa3.1 通道阻断剂。
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