VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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2,4-Diamino-6-hydroxypyrimidine是Inhibit tetrahydrobiopterin synthesis,thus NOS activity。
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1-Deoxymannojirimycin hydrochloride是α-Mannosidase I 抑制剂。
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17-ODYA是LTB ω-hydroxylase 抑制剂。
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1400W dihydrochloride是活性的 高选择性 iNOS 抑制剂。
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1,9-Dideoxyforskolin是Forskolin的非活性类似物。
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