VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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4,4-Pentamethylenepiperidine hydrochloride是M2 proton 通道阻断剂。
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3-Nitropropionic acid是不可逆的 mitochondrial respiratory complex II 抑制剂。
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3-Bromo-7-nitroindazole是选择性 nNOS 抑制剂。
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3,5-DHBA是选择性 HCA1 激动剂。
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2-Palmitoylglycerol是内源性脂类, 加强 2-arachidonylglycerol 的活性。
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