VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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BIIE 0246是活性的,选择性非肽类 NPY Y2 受体拮抗剂。
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BIBP 3226 trifluoroacetate是Mixed NPY Y1和NPFF 受体拮抗剂。
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BIBO 3304 trifluoroacetate是高 选择性 NPY Y1 受体拮抗剂。
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BIBN 4096是活性的,选择性 CGRP 受体拮抗剂。
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BI 9564是活性的,选择性 BRD9,BRD7 抑制剂, 口服有效。
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