VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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BMS 309403是活性的,选择性 FABP4 抑制剂。
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BMS 303141是ATP citrate lyase 抑制剂, 口服活性。
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BMS 193885是活性的, 竞争性 NPY Y1 受体拮抗剂。
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BIX NHE1 inhibitor是活性的,选择性 NHE1 抑制剂。
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BIRT 377是 LFA-1的活性的阴性变构的调节剂。
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