VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Wedelolactone is a multi-target natural plant coumestan exhibiting cytotoxicity towards cancer cells. Wedelolactone acts as an inhibitor of chymotrypsin-like, trypsin-like, and caspase-like activities of proteasome in breast cancer cells.
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Trospium chloride (Sanctura) is a competitive muscarinic cholinergic receptor antagonist.
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L-ornithine具有抗疲劳作用, 促进氨的排泄。
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Eflornithine hydrochloride, hydrate is a drug found to be effective in the treatment of facial hirsutism.
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Amifostine is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.
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