VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 
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    Deferoxamine mesylate是铁螯合剂,缺氧模拟剂(hypoxia mimetic agents)。

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  • DCPIB EI0942

    DCPIB是VSAC/ICl的选择性阻断剂会在各种心血管组织中肿胀。抑制葡萄糖诱导的胰岛素释放(glucose-stimulated)。

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  • DAU 5884 hydrochloride EI0935

    DAU 5884 hydrochloride是M3 受体拮抗剂。

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  • D-AP4 EI0929

    D-AP4是广谱EAA 拮抗剂。

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  • Damnacanthal EI0925

    Damnacanthal是活性选择性 p56lck 抑制剂,也是LIMK1/2 抑制剂。

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