VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Epoprostenol是内源性 IP 受体激动剂。
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EML 425是可逆的非竞争性 p300/CBP 抑制剂(reversible and non-competitive)。
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EMD 66684是活性选择性非肽类AT1 拮抗剂。
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EIT hydrobromide是选择性 iNOS 抑制剂,作用于精氨酸键和位点(arginine binding site.)。
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EG 00229是Neuropilin 1 (NRP1) 受体拮抗剂,抑制 VEGFA和NRP1的结合。
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