VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 
  • GGsTop EI1179

    GGsTop是γ-glutamyl transpeptidase (GGT)的抑制剂。

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  • GC 1 EI1177

    GC 1是高亲和性thyroid receptor α (TRα),TRβ 激动剂,拟甲状腺素(thyromimetic)。

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  • Gavestinel EI1172

    Gavestinel是活性选择性的甘氨酸位点拮抗剂(orally available and active in vivo)。

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  • Garcinol EI1170

    Garcinol是PCAF/p300 抑制剂抗肿瘤活性。

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  • Galloflavin EI1164

    Galloflavin是Lactate dehydrogenase 抑制剂, 削弱有氧糖酵解(impairing aerobic glycolysis)。

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