VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Garcinol是PCAF/p300 抑制剂抗肿瘤活性。
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Galloflavin是Lactate dehydrogenase 抑制剂, 削弱有氧糖酵解(impairing aerobic glycolysis)。
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G 28UCM是FASN 抑制剂。
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Furamidine dihydrochloride是选择性 PRMT1 抑制剂。
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Fumonisin B1是Sphingosine N-acyltransferase抑制剂。
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