VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Laetrile is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds.Amygdalin isolated from S. Persicae extract in ISF-1 through a bioactivity-guided fractionation procedure induced the expression of follistatin in HepG2 and C2C12 cell lines.The amygdalin induced increase in TCCSUP migratory behavior indicates that any anti-tumor benefits from amygdalin (seen with the other two cell lines) may depend upon the cancer cell type.Amygdalin is a natural product that owns antitumor activity, less side effects, widely sourced and relatively low priced.
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Zafirlukast (扎鲁司特) 是口服活性的白三烯受体拮抗剂（LTRA）。
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